产品货号：
Z19197
中文名称：
LGI4抗体
英文名称：
Anti-LGI4 Antibody
产品规格：
0.1mg
发货周期：
1～3天
产品价格：
询价
| 抗体名称 | Anti-LGI4 Antibody |
| 指标别名 | LGIL3,LGIL3,UNQ6515/PRO21485,Leucine-rich repeat LGI family member 4,LGI1-like protein 3 |
| 克隆性 | Polyclonal |
| 检验物种 | human,mouse,rat |
| 应用范围 | ELISA,WB |
| 基因名称 | LGI4 |
| 抗体来源 | Rabbit |
| 抗体类型 | IgG |
| 免疫原 | LGI4 antibody was raised against a 17 amino acid synthetic peptide from near the carboxy terminus of human LGI4.The immunogen is located within amino acids 470 - 520 of LGI4. |
| 计算分子量 | 59kDa |
| 成分 | LGI4 Antibody is supplied in PBS containing 0.02% sodium azide. |
| 纯化方式 | LGI4 Antibody is affinity chromatography purified via peptide column. |
| 浓度 | 1mg/mL |
| 产品形态 | 溶液 |
| 保存条件 | 4℃可保存3个月，-20℃可保存1年。 |
| 背景资料 | The leucine-rich,glioma inactivated gene 4 (LGI4) is a member of the LGI family in which LGI1 is the exemplar.The LGI family consists of four of highly related proteins containing leucine-rich repeats (LRRs) which are highly similar to other transmembrane signaling molecules and receptors.LGI1 has been identified as a candidate tumor suppressor gene for glioma and plays a role in autodominant lateral temporal epilepsy (ADTLE),an epileptic syndrome characterized by focal seizures with predominant auditory symptoms.Despite its high homology with LGI1 and similar pattern of expression,mutations in LGI4 have not been found to be associated with ADTLE.However,the LGI4 gene is located in a region linked to benign familial infantile convulsions.Further study revealed that a GC-to-AT polymorphism was correlated with childhood absence epilepsy.Other studies showed that decreasing LGI4 expression in cultured cells inhibits myelination,indicating that LGI4 may play a role in neural development. |
| Uniprot ID | Q8N135 |
| 基因名全称 | Leucine-rich repeat LGI family,member 4 |
| 蛋白名全称 | Leucine-rich repeat LGI family,member 4 |
| 推荐稀释比 | LGI4 antibody can be used for the detection of LGI4 by Western blot at 1 ～ 2μg/mL.Antibody validated:Western Blot in rat samples.All other applications and species not yet tested. |
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